Description
Form: Lyophilized powder vial | Purity: ≥99% | Storage: Refrigerate
What It Is
5-Amino-1MQ is a small molecule NNMT (Nicotinamide N-methyltransferase) inhibitor. NNMT is an enzyme that becomes overactive in fat tissue during obesity and aging, consuming NAD+ and promoting fat storage. Blocking NNMT restores NAD+ availability and shifts metabolism toward fat burning.
What It Does
5-Amino-1MQ reduces body fat, improves insulin sensitivity, increases NAD+ levels, activates SIRT1 (a longevity protein), and improves mitochondrial function. In animal studies it produced significant fat loss without changes to diet or exercise.
How It Works
By inhibiting NNMT, 5-Amino-1MQ prevents the enzyme from consuming NAD+. This raises intracellular NAD+ levels, which activates sirtuins and AMPK, shifting cellular metabolism toward fat oxidation and away from fat storage.
Who Benefits Most
People with stubborn body fat, especially visceral fat. People with metabolic syndrome or insulin resistance. Anyone who wants to raise NAD+ levels through a different mechanism than direct supplementation.
Cautions
Limited long term human safety data. Use under practitioner supervision. Not recommended during pregnancy. Monitor liver function with extended use.
Pairs Well With
NAD+ for synergistic NAD+ restoration. MOTS-c for comprehensive mitochondrial and metabolic optimization. Retatrutide for aggressive fat loss protocols.
Quality and Sourcing
Every Smart Stack batch is tested for purity, sterility, potency, and identity. Certificates of Analysis are available on request.
- HPLC purity testing
- LC-MS identity confirmation
- Sterility and endotoxin testing
- Heavy metals screening
- Purity: greater than or equal to 99%
For research use only. Not for human consumption. Not for resale. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.









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