Description
Form: Lyophilized powder vial | Purity: ≥99% | Storage: Refrigerate
What It Is
KPV is a tripeptide (Lysine-Proline-Valine) derived from the C-terminal end of alpha-MSH. It retains the anti inflammatory properties of alpha-MSH without the melanocortin receptor activation that produces tanning and sexual effects. It is one of the most targeted anti inflammatory peptides available.
What It Does
KPV reduces systemic and local inflammation, heals the gut lining, reduces intestinal permeability (leaky gut), improves symptoms of inflammatory bowel disease, reduces skin inflammation, and has antimicrobial properties. It is particularly effective for gut-based inflammation and autoimmune conditions with a gut component.
How It Works
KPV enters cells and travels directly to the nucleus where it inhibits NF-kB, the master regulator of inflammatory gene expression. This intracellular mechanism is different from most anti inflammatory compounds, which work extracellularly. It also inhibits inflammatory cytokines including IL-1, IL-6, and TNF-alpha.
Who Benefits Most
People with IBD, Crohn’s disease, ulcerative colitis, or leaky gut. People with autoimmune conditions that have a gut component. Anyone with chronic systemic inflammation. People with skin conditions like psoriasis or eczema.
Cautions
Excellent safety profile. No significant adverse effects reported in research. Not recommended during pregnancy.
Pairs Well With
BPC-157 for comprehensive gut healing and repair. GHK-Cu for skin and tissue support. Wolverine (BPC-157 / TB-500) for systemic repair alongside anti inflammatory support.
Quality and Sourcing
Every Smart Stack batch is tested for purity, sterility, potency, and identity. Certificates of Analysis are available on request.
- HPLC purity testing
- LC-MS identity confirmation
- Sterility and endotoxin testing
- Heavy metals screening
- Purity: greater than or equal to 99%
For research use only. Not for human consumption. Not for resale. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.












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